Iosifescu, Smoller, et al.
Discussed the filtering of the patients from the MDD data mart to select more patients with MRI's to study the effect of SSRI's and SSRI resistance (in combination with a SNP study).
Jordan reviewed what it takes to get the right specificity and sensitivity and chewed over the issue of how in diseases of prevalence less than 5%, the danger to a GWAS may be more at the level of lack of specificity than lack of sensitivity (if as is the case in i2b2 we have a large enough pool of cases).
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