Review of drug exposure methodology

Given intermittent recording of drug exposure and clinical events, there is going to be a lot of censoring in the EHR data stream. This kind of data censoring is a methodological challenge and we reviewed various heuristics and comparisons that can be used to correct/account for this censoring. A lot of focus on modeling the frequency of observations.

Cardiovascular Disease DBP

Shaw, Cai et al.

The performance of the diabetes filter based on 7 variables was reviewed. It was surprisingly good. We then discussed what features NLP would be best applied to and the agreement was that medications would be the highest value in that regard.

Release schedule/Temporal Reasoning

Attending: Kohane, Murphy, Weber, Churchill, Mendis, McGow

Discussed the follow on of our prior discussions on the design of an episode table and an Episode-to-FACT mapping table.

Selection of patients by NLP: reproducibility across institutions

Led by Rheumatoid arthritis DBP

Northwestern, Vanderbilt calling in on Skype.

Reviewed the remarkably good concordance of the performance across several systems.

Open source collaborations

Murphy, Kohane, Weber, Mendis, McGaw, Bickel

Reviewed the growing volume of AUG email related to installing i2b2 (multiple operating systems and RDBMS) and how to be responsive without overwhelming our other developer community support activities.

Discussed improvements to the i2b2 web client and incorporating contributions from the community.

Open source projects etc

Murphy, Weber, Churchill, McGow, Wilson, Kohane, Mendis

Reviewed community.i2b2.org. Specifically the i2b2 webclient as a first instance (this is a project that was first started by Griffin to work on top of the .NET stack) of bringing in a non-core project. Discussed how to prioritize tasks within a sponsored project.

We had an important but tangential discussion about the definition of episodes of care.