CVD-DM DBP

Shaw, Kohane, Gainer. Churchill, Savova, Sordo, Iftikhar Kullo callinh-in from Mayo

Reviewed first how Dr. Kullo et al defined peripheral arterial disease. First without and then with NLP on clinical reports (mostly on interventional radiology and ultrasound to a lesser degree, CT and MRI angiograms). The performance described is remarkable (accuracy in the high 90's).

Selection of patients by NLP: reproducibility across institutions

Led by Rheumatoid arthritis DBP

Northwestern, Vanderbilt calling in on Skype.

Reviewed the remarkably good concordance of the performance across several systems.

NLP

Temporal Reasoning

Mendis, Bickel, Kohane, Weber, Murphy

Lots of back and forth about representing multiple versions/depictions of episode in patient selection. Discussion of which tables will bear the additional complexity.

Autoimmune CVD DBP

Murphy, Karlsson. Gainer, Shaw, Savova, Szolovits, Liao, Kohane, Churchill, Cai,

Discussed the NLP annotation pipeline (used by the "gold standard" annotators).

Discussed predictors of RA (by NLP and codified data) in patients who previously did not qualify as having RA.

CVD & DM DBP

Shaw, Savova, Liao, Churchill, Murphy, Gainer, Sordo, Kohane

Discussed how to learn lessons from other NLP CVD efforts that Guergana has been involved in (e.g. the eMERGE applications of her cTAKES framework). Discussed the addition of echocardiogram data.

Open source collaborations

Murphy, Kohane, Weber, Mendis, McGaw, Bickel

Reviewed the growing volume of AUG email related to installing i2b2 (multiple operating systems and RDBMS) and how to be responsive without overwhelming our other developer community support activities.

Discussed improvements to the i2b2 web client and incorporating contributions from the community.