Friday, January 16, 2009

Major Depressive Disorder

Qing, Zak, Susanne, Shawn, Jordan, Roy, Griffin, Dan, Vivian

Discussed the definition of normality for the imaging controls and how far back in time we could pull normal MRI's.

Reviewed the validation methodology for cohort ascertainment. This include the review of the flow from the original RPDR database all the way through the various NLP filters and human validation steps. Clear consensus that we need to focus on Positive Predictive Value and Negative Predictive Value. Significant discussion of what constitutes a positive case.

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