Weber, Griffin, Mendis, Kohane, Churchill, McGow
Griffin committed to elaborating the tempotral query workflow over the next two months using UI mockups intended to drive our back end architecting of the interval/point representations and episode of care. Goal is a firm perspective on the
Thin client UI extensions. Discussed workflow dependencies.
Visiting: John Pestian
Also: Ozlem, Guergana, Margharita, Szolovits, Kohane, Churchill
Discussed a clinical corpus of victims of suicide and how to approach the NLP task in this horribly at risk population. Also discussed several evaluation strategies.
Gainer, Cai, Savova, Ashwin, Plenge, Sordo, Kohane, Raychaudri, Karlson
Focus on Inflammatory Bowel disease today.
Reviewed disease itself: Peak incidence:14-24 (second peak between 50-70 years).
Not an autoimmune disease (auto-antibodiesa not found against human antigens) but the immune system plays an important pathogenic role. Smoking is an important risk factor for IBD but in very specific ways:
Past smoking increases risk of ulcerative colitis but current smoking increases the risk of Crohn's disease.
Reviewed previously implicated genes in linkage and GWAS studies. Reviewed clinical course and treatment. Reviewed epidemiological evidence regarding cardiovascular disease in IBD.
Concluded with a discussion of the IBD component of the auto-immune-CVD datamart.
Attending: Kohane, Murphy, Weber, Churchill, Mendis, McGow
Discussed the follow on of our prior discussions on the design of an episode table and an Episode-to-FACT mapping table.
Shaw, Kohane, Gainer. Churchill, Savova, Sordo, Iftikhar Kullo callinh-in from Mayo
Reviewed first how Dr. Kullo et al defined peripheral arterial disease. First without and then with NLP on clinical reports (mostly on interventional radiology and ultrasound to a lesser degree, CT and MRI angiograms). The performance described is remarkable (accuracy in the high 90's).
Led by Rheumatoid arthritis DBP
Northwestern, Vanderbilt calling in on Skype.
Reviewed the remarkably good concordance of the performance across several systems.
